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WHAT IS ESTRADIOL (E2)?
Estradiol (E2) is one of three estrogen hormones naturally produced in the body. Men and women have estradiol, but women have much higher hormone levels than men.
Estradiol controls the distribution of fat in the body of women. It is less common in men. The purpose of this hormone is to protect the reproductive system. Increased levels of estradiol during the menstrual cycle cause the egg to mature and be released, and the uterine lining to thicken to allow the fertilized egg to implant. It is a hormone made in the ovaries.
It decreases as women age, and decreases during menopause. In men, this hormone is beneficial for bones, helping nitric oxide production and brain function.
WHAT ARE THE SYMPTOMS OF LOW ESTRADIOL?
Fatigue, depression, attention problems, hot flashes, weakness, frequent urinary tract infections, irregular menstruation, vaginal dryness are the symptoms of low estradiol level.
WHAT ARE THE SYMPTOMS OF ESTADIOL HIGH?
Early puberty, breast development problems in boys, discomfort in the ovaries or testicles are among the symptoms of high estradiol.
HOW IS ESTRADIOL LEVEL MEASURED?
It can be measured with a blood test. Its other name is E2. The doctor may order this test if they suspect a problem with a high or low E2 level. These problems can be listed as follows:
– Menstrual problems
– Ovarian tumors
– Gynecomastia in men
– Menopausal symptoms
– Breast cancer
During puberty, this test can also be done to diagnose precocious puberty. Along with E2, FSH and LH values, TSH/FT4, prolactin values can also be checked.
HOW MUCH ESTADIOL LEVEL SHOULD BE?
Results are given in picograms per milliliter (pg/mL). Normal levels for estradiol:
– 30 to 400 pg/mL for premenopausal women
– 0 to 30 pg/mL for postmenopausal women
– 10 to 50 pg/mL for men
If the results are lower, it could mean ovarian failure, also called premature menopause, or low estrogen due to rapid weight loss or anorexia.
If the results are higher, it may suggest a tumor in the ovaries, testicles, or adrenal glands.
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